Think in destination markets
TYS lists airport routes, but travelers usually care about cities and trip regions. We group multiple airports into one market when that makes the decision clearer.
Current Knoxville nonstop network
Where can you fly nonstop from Knoxville?
The simple current list of airport destinations served nonstop from McGhee Tyson Airport.
The short answer
35 nonstop airport destinations are on the current official TYS list.
Some destination cities have more than one airport, so the number of airports is not always the same as the number of destination cities.
How to use Knoxville's nonstop network
Compare multi-airport cities
7 current destination markets have more than one relevant nonstop airport from Knoxville. Airport choice can change fare, airline and ground transportation.
Check actual dates
Being on the nonstop network does not mean a route operates every day. Open the destination guide and search live dates before building the trip around it.
Browse by trip type
Florida nonstop flights
Compare Orlando, South Florida, Tampa Bay, Gulf Coast and Keys options.
Weekend trips
See recent nonstop weekend examples and compare fare vs. flight time.
Beach destinations
Choose by coast, airport and ground distance—not airfare alone.
New nonstop routes
See recently launched routes that remain on the current network.
Browse nonstop destinations by region
Florida
- Destin / Fort Walton Beach — VPS
- Fort Lauderdale — FLL
- Jacksonville — JAX
- Key West — EYW
- Miami — MIA
- Orlando — MCO, SFB
- Punta Gorda — PGD
- Sarasota / Bradenton — SRQ
- Tampa Bay — TPA, PIE
Northeast & Mid-Atlantic
- Baltimore — BWI
- Boston — BOS
- New Haven — HVN
- New York — LGA, EWR
- Philadelphia — PHL
- Washington, D.C. — DCA, IAD
Midwest & Great Lakes
- Chicago — ORD, MDW
- Detroit — DTW
- Minneapolis / St. Paul — MSP
Texas
West & Mountain
Southeast
- Atlanta — ATL
- Charlotte — CLT
- Gulf Shores / Orange Beach — GUF
- Nashville — BNA
All current nonstop airports
- Atlanta (ATL)
- Austin (AUS)
- Nashville (BNA)
- Boston (BOS)
- Baltimore (BWI)
- Charlotte (CLT)
- Dallas-Love Field (DAL)
- Washington D.C.-Reagan (DCA)
- Denver (DEN)
- Dallas-Fort Worth (DFW)
- Detroit (DTW)
- Newark (EWR)
- Key West (EYW)
- Fort Lauderdale (FLL)
- Gulf Shores / Orange Beach (GUF)
- Houston-Hobby (HOU)
- New Haven (HVN)
- Washington D.C.-Dulles (IAD)
- Houston-George Bush (IAH)
- Jacksonville (JAX)
- Las Vegas (LAS)
- New York-LaGuardia (LGA)
- Orlando-International (MCO)
- Chicago-Midway (MDW)
- Miami (MIA)
- Minneapolis-Saint Paul (MSP)
- Chicago-O'Hare (ORD)
- Punta Gorda (PGD)
- Philadelphia (PHL)
- Phoenix (PHX)
- St. Petersburg / Tampa Bay (PIE)
- Orlando-Sanford (SFB)
- Sarasota / Bradenton (SRQ)
- Tampa (TPA)
- Destin-Ft. Walton Beach (VPS)
Airlines on the current nonstop network
Allegiant Air
American Airlines
Avelo Airlines
Delta Air Lines
Southwest Airlines
United Airlines
Explore Knoxville flight topics
Route information last checked: 2026-10-28. Current nonstop-route status is based onMcGhee Tyson Airport's official nonstop destination list. Individual airline schedules can change.See how we verify flight information →