Where can I fly nonstop from Knoxville this weekend?
22 cities: Atlanta, Austin, Baltimore, Boston, Charlotte, Chicago, Dallas, Denver, Detroit, Fort Lauderdale, Houston, Key West, Las Vegas, Miami, Minneapolis / St. Paul, Nashville, New York, Orlando, Philadelphia, Punta Gorda, Tampa Bay and Washington, DC.
These cities have a nonstop leaving Knoxville this Friday or Saturday and a nonstop back on Sunday or Monday. Leaving Friday, October 30 or Saturday, October 31, back Sunday, November 1 or Monday, November 2.
- Atlanta ATL
- Austin AUS
- Baltimore BWI
- Boston BOS
- Charlotte CLT
- Chicago ORD / MDW
- Dallas DFW / DAL
- Denver DEN
- Detroit DTW
- Fort Lauderdale FLL
- Houston IAH / HOU
- Key West EYW
- Las Vegas LAS
- Miami MIA
- Minneapolis / St. Paul MSP
- Nashville BNA
- New York LGA / EWR
- Orlando MCO / SFB
- Philadelphia PHL
- Punta Gorda PGD
- Tampa Bay TPA / PIE
- Washington, DC DCA / IAD
Common questions
Where can I fly nonstop from Knoxville for a weekend?
Atlanta, Austin, Baltimore, Boston, Charlotte, Chicago, Dallas, Denver, Detroit, Fort Lauderdale, Houston, Key West, Las Vegas, Miami, Minneapolis / St. Paul, Nashville, New York, Orlando, Philadelphia, Punta Gorda, Tampa Bay and Washington, DC.
More ways to browse
Flight days and times last checked Wednesday, October 28, 2026 using Google Flights. We check every week. The list of nonstop destinations comes from McGhee Tyson Airport's official nonstop list (checked October 26, 2026).Schedules can change, so always confirm your exact flight with the airline. How we check flights.